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ISSN 2522-9028 (Print)
ISSN 2522-9036 (Online)
DOI: https://doi.org/10.15407/fz

Fiziologichnyi Zhurnal

is a scientific journal issued by the

Bogomoletz Institute of Physiology
National Academy of Sciences of Ukraine

Editor-in-chief: V.F. Sagach

The journal was founded in 1955 as
1955 – 1977 "Fiziolohichnyi zhurnal" (ISSN 0015 – 3311)
1978 – 1993 "Fiziologicheskii zhurnal" (ISSN 0201 – 8489)
1994 – 2016 "Fiziolohichnyi zhurnal" (ISSN 0201 – 8489)
2017 – "Fiziolohichnyi zhurnal" (ISSN 2522-9028)

Fiziol. Zh. 2018; 64(1): 47-51


CHANGES IN THE CELLULAR LINK OF THE IMMUNE SYSTEM IN INFERTILE MEN AT THE TOXOCARIASIS INVASION

L.L. Vorontsova, M.I. Dub, V.A. Kovalenko

    State establishment “Zaporizhzhya Medical Academy of Post Graduate Education Ministry of Health of Ukraine”, Zaporizhzhya, Ukraine
DOI: https://doi.org/10.15407/fz64.01.047

Abstract

The state of the cellular link of the immune system was studied in 89 men aged 20 to 45 years without and with reproductive disorders. All men underwent a comprehensive study, including determining the level of fragmentation of sperm DNA, the presence of toxocariasis invasion, as well as evaluating the specific link of the immune system. We observed multidirectional changes in the cellular link of specific immunity, depending on the level of immunoglobulins G against toxocariasis antigens, from hyperreactivity to immunosuppression in infertility men. It has been established that the number of fragmented spermatozoa is affected both by the state of the immune system and by the residence of men with a violation of reproductive function under adverse environmental conditions. Thus, infertile men, who lives in the territory of Zaporizhzhya and the region, are characterized by violations of the immune status, and toxocariasis invasion makes certain changes in the state of the immune system, namely, in the cellular link.

Keywords: cellular link of the immune system; toxocariasis invasion; fragmentation of sperm DNA; male infertility.

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