Українська English

ISSN 2522-9028 (Print)
ISSN 2522-9036 (Online)
DOI: https://doi.org/10.15407/fz

Fiziologichnyi Zhurnal

is a scientific journal issued by the

Bogomoletz Institute of Physiology
National Academy of Sciences of Ukraine

Editor-in-chief: V.F. Sagach

The journal was founded in 1955 as
1955 – 1977 "Fiziolohichnyi zhurnal" (ISSN 0015 – 3311)
1978 – 1993 "Fiziologicheskii zhurnal" (ISSN 0201 – 8489)
1994 – 2016 "Fiziolohichnyi zhurnal" (ISSN 0201 – 8489)
2017 – "Fiziolohichnyi zhurnal" (ISSN 2522-9028)

Fiziol. Zh. 2017; 63(6): 60-65

REGULATION MECHANISMS OF CORTISOL LEVEL IN PIGS’ BLOOD SERUM UNDER STRESS

O. V. Danchuk, V. I. Karpovskyі, V. О. Trokoz, R. V. Postoі

    National University of Life and Environmental Sciences of Ukraine, Kyiv, Ukraine
DOI: https://doi.org/10.15407/fz63.06.060


Abstract

The results of investigation the relationship and mutual influence of main features of cortical processes with cortisol level in pigs’ blood serum under technological stress are shown. Technological stress is accompanied by increase concentrations of this hormone in pigs’ blood serum in 2.3–2.7 times depending on the typological characteristics of its nervous system. In animals of weak type of higher nervous activity during one month after exposure to technological stimulus the cortisol level was significantly higher from such in animals of strong types of higher nervous activity. Stress affects (F=1803>FU=2.2; P<0.001) the content of this hormone in pigs’ blood serum more than the type of higher nervous activity (F=45.1>FU=2.27; P<0.001). With increase of strength and balance of cortical processes the cortisol level in blood of animals decreases (r=-0.58–0.76; P<0.01–0.001). Established the significant interaction between typological features of higher nervous activity and technological stimulus (F=38.8>FU=1.76; P<0.001), which indicates a possible change in the strength, balance and mobility of the nervous processes under the influence of the stress factor.

Keywords: Cortisol, higher nervous activity, pigs, stress

Full text: (PDF, in Ukrainian)

References

  1. Ivanyra IO. Dynamics of the adaptation of the body of students with different typological properties of higher nervous activity to physical activity. Visn Probl Biol i Med. 1999;11:28-34. [Ukrainian].
    2.  
  2. Karpovskyi VI, Trokoz VO, Danchuk OV, Postoi RV, Karpovskyi VV, Vasyliv AP. The influence of the main cortical processes on the productivity of pigs during the period of technological stress. Ekolog i Zhivotn Mir. 2016;2:8-13. [Ukrainian].
    3.  
  3. Makarenko MV, Lizogub VS, Kozhemyako TV, Chernenko NP. Age peculiaritys of the centralinformation processing speed among the persons with the different level of the nervousprocessing functional mobility. Fiziol Zh. 2011;57(1):88-93. [Ukrainian]. PubMed
    4.  
  4. Makarenko MV, Golyaka SK. Individual-typological qualities of the higher nervous activity and sensomotor reactions in students with different level of sport qualifications. Fiziol Zh. 2005;51(4):70-74. [Ukrainian]. PubMed
    5.  
  5. Makarenko NV, Lisogub VS, Yuchimenko LI. Heart rhythm of students with differentindividual - typological characteristics of the higher nervous activity at examination stress. Fiziol Zh. 2003;49(1):28-33. [Ukrainian]. PubMed
    6.  
  6. Danchuk VV, Danchuk AV, Tsepko NL. Oxidative stress - pathology or adaptation? Tvarynnytstvo Ukrainy. 2004;4:21-23. [Ukrainian].
    7.  
  7. Tokarchuk KO, Kapustyanenko LG, Shandrenko SG. The role of aldehydes in development of oxidative stress under rhabdomyolysis in rats. Fiziol Zh. 2013;59(1):25-32. [Ukrainian). PubMed
    8.  
  8. Nosenko ND, Tarasenko LV, Sinitsyn PV, Sachinskaya OV, Ganzhiy IY, Reznikov AG. The dynamics of hormonal changes in female rats exposed to chronic stress and androgen excess during pubescence. Fiziol Zh. 2012;58(3):3-9. [Ukrainian]. PubMed
    9.  
  9. Sahach VF, Andrukhov OI. The effect of nitric oxide on the contractile activity of skinned preparations of the smooth muscles of the rat portal vein. Fiziol Zh. 2000;46(1):3-9. [Ukrainian].
    10.  
  10. Kopanitsia MV, Boichuk IaA, Lozova NO, Kryshtal OO. Interneuronal signaling mediated by the trans-synaptic diffusion of neurotransmitters. Fiziol Zh. 1999;45(4):132-47. [Ukrainian]. PubMed
    11.  
  11. Karpovskyi PV, Karpovskyi VV, Trokoz AV, Landsman AA, Skrypkina VN, Postoi RV, Kryvoruchko DI, Trokoz VO, Karpovskyi VI. Cortico-vegetative regulation of relations in the physiological functions of pigs. Biolohiia Tvaryn. 2015;17(2):65-73. [Ukrainian].
    12.  
  12. Trokoz VO, Karpovskyi VI, Trokoz AV, Puzir VV, Vasyliv AP, inventors, NULES of Ukraine, assignee. Method of determining the types of higher nervous activity pigs. Ukraine. Pat. 70344. 2012 June 11. [Ukrainian].
    13.  
  13. Naumenko VV. Some features of higher nervous activity and types of the nervous system in pigs [dissertation abstract] Lviv: LNUVM named after SZ Gzhytskogo; 1968. 36 p.
    14.  
  14. Pavlov IP. Physiological teaching about types of the nervous system, temperaments too. 3rd ed. Moscow, Leningrad: Akademiia nauk SSSR;1949. 439. [Russian].
    15.  
  15. Cocchi M, Sardi L, Tonello L, Martelli G. Do mood disorders play a role in pig welfare? Ital J Animal Sci [Internet]. 2009;8:4,691-704. CrossRef  
  16. Antelman SM, Chiodo LA. Stress: its effect on interaction among biogenic amines and role in the induction and treatment of diseases. In Iverson LS, Iverson SD, Snayder SH eds. Handbook of Phychopharmacology, 18th ed. New York: Plenum Press, 1984. p. 279 -341. CrossRef  
  17. Tarasov II. Stress syndrome in pigs. Selskoe hozyaystvo za rubezhom. 1982;4:47-49.
    18.  
  18. Frankova I. Life on the brink: social stress, trauma and psychopathology. Psychosom Med and Gen Pract [Internet]. 2017 Jan; 2(1):020115. CrossRef  
  19. Frankova, I. "Life on the Brink: Social Stress, Trauma and Psychopathology". Psychosomatic Medicine and General Practice, Vol. 2, no. 1, Jan. 2017, p. e020115, CrossRef  
  20. Usenko SO. Hormonal and biochemical status of blood serum of pigs of different age, sex and physiological state [dissertation]. Poltava: UAAN, In-t svinarstva Im. O. V. Kvasnitskogo; 2004. 151.
    21.  
  21. Soetanto A, Wilson RS, Talbot K, Un A, Schneider JA, Sobiesk M, Kelly J, et al. Association of anxiety and depression with microtubule-associated protein 2-and synaptopodin-immunolabeled dendrite and spine densities in hippocampal CA3 of older humans. Arch Gen Psychiatry [Internet]. 2010;67(5):448-457. CrossRef PubMed PubMedCentral
    22.  
  22. Neumann ID, Slattery DA. Oxytocin in General Anxiety and Social Fear: A Translational Approach. Biol Psychiatry. 2016;79(3):213-21. CrossRef PubMed
© National Academy of Sciences of Ukraine, Bogomoletz Institute of Physiology, 2014-2024.