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ISSN 2522-9028 (Print)
ISSN 2522-9036 (Online)

Fiziologichnyi Zhurnal

is a scientific journal issued by the

Bogomoletz Institute of Physiology
National Academy of Sciences of Ukraine

Editor-in-chief: V.F. Sagach

The journal was founded in 1955 as
1955 – 1977 "Fiziolohichnyi zhurnal" (ISSN 0015 – 3311)
1978 – 1993 "Fiziologicheskii zhurnal" (ISSN 0201 – 8489)
1994 – 2016 "Fiziolohichnyi zhurnal" (ISSN 0201 – 8489)
2017 – "Fiziolohichnyi zhurnal" (ISSN 2522-9028)

Fiziol. Zh. 1999; 45(1-2): 26-34

The effect of selective serotonin administration into different portions of the coronary vascular bed on the retrograde (collateral) coronary blood flow in myocardial ischemia in dogs

Azarov VI, Hrabovs'kyĭ LO, Moĭbenko OO.

    A. A. Bogomoletz Institute of Physiology, NAS, Ukraine.


The purpose of the present investigation was to determine the action of intra-coronary infusion of serotonin on collateral blood flow in dog heart. Intra-coronary injection of serotonin elicited a cardiogenic hypertensive chemoreflex and transient but marked reductions of collateral blood flow. The cardiac and circulatory effects of the hypertensive cardiogenic chemoreflex and reductions of collateral blood flow abolished by sectioning of the cervical vagi. These data indicate that serotonin act on blood flow in collateral-dependent tissue of ischemic dog heart.


© National Academy of Sciences of Ukraine, Bogomoletz Institute of Physiology, 2014-2024.