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ISSN 2522-9028 (Print)
ISSN 2522-9036 (Online)

Fiziologichnyi Zhurnal

is a scientific journal issued by the

Bogomoletz Institute of Physiology
National Academy of Sciences of Ukraine

Editor-in-chief: V.F. Sagach

The journal was founded in 1955 as
1955 – 1977 "Fiziolohichnyi zhurnal" (ISSN 0015 – 3311)
1978 – 1993 "Fiziologicheskii zhurnal" (ISSN 0201 – 8489)
1994 – 2016 "Fiziolohichnyi zhurnal" (ISSN 0201 – 8489)
2017 – "Fiziolohichnyi zhurnal" (ISSN 2522-9028)

Fiziol. Zh. 1999; 45(3): 79-86

The characteristics of the metabolic and psychophysiological disorders in patients in different stages of chronic alcoholism

Kharchenko NK.

    Ukrainian Scientific-Research Institute of Social and Forensic Psychiatry, Ministry of Public Health of Ukraine, Kiev


The content of endogenic ethanol (EE) and acetaldehyde (AcA) in blood, excretion of catecholamines (CA) with urine and their content in blood, functional activity of vegetative nerve system and central nerve system were studied in patients with chronic alcoholism in the period of short-term remission. It is shown that the formation and development of chronic alcoholism is accompanied by the shift of the relation AcA/EE towards the progressive accumulation of AcA, disturbances in CA metabolism, shifts in the activity of vegetative nerve system and CNS. Data obtained in the work evidence for the important role of disturbances in metabolic processes (especially E metabolism, as well as CA) in pathogenesis of alcohol dependence.


© National Academy of Sciences of Ukraine, Bogomoletz Institute of Physiology, 2014-2024.