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ISSN 2522-9028 (Print)
ISSN 2522-9036 (Online)

Fiziologichnyi Zhurnal

is a scientific journal issued by the

Bogomoletz Institute of Physiology
National Academy of Sciences of Ukraine

Editor-in-chief: V.F. Sagach

The journal was founded in 1955 as
1955 – 1977 "Fiziolohichnyi zhurnal" (ISSN 0015 – 3311)
1978 – 1993 "Fiziologicheskii zhurnal" (ISSN 0201 – 8489)
1994 – 2016 "Fiziolohichnyi zhurnal" (ISSN 0201 – 8489)
2017 – "Fiziolohichnyi zhurnal" (ISSN 2522-9028)

Fiziol. Zh. 1999; 45(3): 74-78

The phenomenon of endotoxicosis in patients with profuse hemorrhages studied by a bioassay method using an isolated preparation of the portal vein from a white rat

Ivashkevych HA, Pryĭma OB, Ivasivka SV, Baiev IeIa.

    Truskavets Municipal Hospital, Kiev


Conceptual question of the blood losses connected with phenomenon of endotoxicosis is being studied in this work. For this purpose an adapted method of the patients' blood having blood losses was used. It was realised on the white rat's vein porta. Ten patients with different kinds of haemorrhage being investigated, the presence of toxic traces in the blood taken from the patients in the first days of the posthaemorrhagic period are evident. The date of the blood toxic are normalised on the tenth-fourteenth day of the posthaemorrhagic period. Toxic features of the patients' blood with blood losses are proved by the investigations of leucocyte index intoxication in the first day of the posthaemorrhagic period. Twenty patients were investigated by that. The received results proved the presence of endotoxicosis in the patients' having blood losses.


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