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ISSN 2522-9028 (Print)
ISSN 2522-9036 (Online)
DOI: https://doi.org/10.15407/fz

Fiziologichnyi Zhurnal

is a scientific journal issued by the

Bogomoletz Institute of Physiology
National Academy of Sciences of Ukraine

Editor-in-chief: V.F. Sagach

The journal was founded in 1955 as
1955 – 1977 "Fiziolohichnyi zhurnal" (ISSN 0015 – 3311)
1978 – 1993 "Fiziologicheskii zhurnal" (ISSN 0201 – 8489)
1994 – 2016 "Fiziolohichnyi zhurnal" (ISSN 0201 – 8489)
2017 – "Fiziolohichnyi zhurnal" (ISSN 2522-9028)

Fiziol. Zh. 2017; 63(2): 34-39

MORPHOFUNCTIONAL STATE OF MAST CELLS IN HYPERHEPARINEMIA IN RATS

S. Kotiuzhynska, A. Gozhenko, D. Umanskyi

    Odessa National Medical University
DOI: https://doi.org/10.15407/fz63.02.034


Abstract

A clear relationship between the functional state of mast cells and the heparin level in plasma in experimental hyperlipidemia in rats has been revealed. It was shown that long-term lipid load increases the activity and number of secretory mast cells. We show the ability of mast cells to deposit the excess of heparin when it is in the organism, that is evidenced by an increase in the number of cells with high saturation level (59,16±3,42% vs 33,54±3,27%) with the simultaneous decline in the number of cells with moderate saturation level (by 40,63 %) with the simultaneous increase of saturation index. Relative to control group.

Keywords: mast cells, heparin, experimental hyperlipidemia.

Full text: (PDF, in Ukrainian)

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