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ISSN 2522-9028 (Print)
ISSN 2522-9036 (Online)
DOI: https://doi.org/10.15407/fz

Fiziologichnyi Zhurnal

is a scientific journal issued by the

Bogomoletz Institute of Physiology
National Academy of Sciences of Ukraine

Editor-in-chief: V.F. Sagach

The journal was founded in 1955 as
1955 – 1977 "Fiziolohichnyi zhurnal" (ISSN 0015 – 3311)
1978 – 1993 "Fiziologicheskii zhurnal" (ISSN 0201 – 8489)
1994 – 2016 "Fiziolohichnyi zhurnal" (ISSN 0201 – 8489)
2017 – "Fiziolohichnyi zhurnal" (ISSN 2522-9028)

Fiziol. Zh. 2016; 62(4): 60-65

DEPENDENCE OF LEVEL OF MYELOPEROXIDASE OF PLASMA OF BLOOD ON FUNCTIONAL STATE OF NEUTROPHILS AT ACUTE INFARCT OF MYOCARDIUM

T.I. Gavrilenko , N.O. Ryzhkova , O.M. Parkhomenko

    National Scientific Center «M.D. Strazhesko Institute of Cardiology, MAS of Ukraine»
DOI: https://doi.org/10.15407/fz62.04.060


Abstract

The purpose of this work was to define dependence of maintenance of myeloperoxidase (MPO) in plasma of blood of patients by the acute infarct of myocardium from the state of oxygen metabolism of neutrophils, which was estimated on activity of myeloperoxidases, superoxid-anion and catalase in cells and on maintenance by peroxigens . 19 is inspected practically healthy volunteers and 56 patients with the the acute infarct of myocardium. The got results testify that maintenance of MPO in plasma of blood of patients with acute infarct of myocardium depends on the functional state of neutrophils, which, in its turn, is related to the clinical features of patients. Low maintenance is associated exceptionally with low activity of MPO of neutrophils, and also other oxygen radicals. High maintenance of MPO in plasma accompanied low or high activity of MPO of neutrophils and is pathognomonic for patients with the acute infarct of myocardium.

Keywords: acute infarct of myocardium; myeloperoxidase; neutrophils.

Full text: (PDF, in Ukrainian)

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