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ISSN 2522-9028 (Print)
ISSN 2522-9036 (Online)
DOI: https://doi.org/10.15407/fz

Fiziologichnyi Zhurnal

is a scientific journal issued by the

Bogomoletz Institute of Physiology
National Academy of Sciences of Ukraine

Editor-in-chief: V.F. Sagach

The journal was founded in 1955 as
1955 – 1977 "Fiziolohichnyi zhurnal" (ISSN 0015 – 3311)
1978 – 1993 "Fiziologicheskii zhurnal" (ISSN 0201 – 8489)
1994 – 2016 "Fiziolohichnyi zhurnal" (ISSN 0201 – 8489)
2017 – "Fiziolohichnyi zhurnal" (ISSN 2522-9028)

Fiziol. Zh. 2001; 47(4): 25-29


Jezzini adnan abbas changes in post-traumatic locus host defensein patients during conservative treatment

A.A.timopeev, E.V.gorobets, A.G.portnychenko, K.V.rozova, M.M.seredenko,V.I. Portnichenko,

    А.А. Bogomoletz Institute of Physiology, NASof Ukraine; Shupyk Kiev Medical Academy ofPost-graduation Education


Abstract

Clinical investigation have been done in adult patients with broken mandible during 3 weeks of conservative treatment with aluminum splints (1st group, n=17) or steel splints (2nd group, n=16) in comparison with health adults (control group, n=18). The neutrophil emigration into alterative locus and their degranu- lation as well as phagocytic activity of peripheral blood neutrophils were tested. It was found that aluminum splint application caused the intensive inflammation and then the depression of local host defense reactions. Treatment with steel splints did not lead to neutrophil function depletion or to hyper-intensification of inflam- matory reaction in patients. The increased values of neutrophil reactions were normalized in this group at the final period of the treatment. The examined trial ensures our accurate method in treatment of patients with broken mandible. The determination of local host defense state may be proposed as preferable simple express-method of evaluation of immune status, treat- ment efficiency and prognosis in these patients.

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© National Academy of Sciences of Ukraine, Bogomoletz Institute of Physiology, 2014-2018.