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Changes in the elastolytic system of blood serumand tissue of aorta associated with acid-base imbalance
..M.trofimova, V.E.dosenko, YU.V.byts
A.A. Bogomoletz National Medical UniversityMinistry of Public Health of Ukraine, Kiev
Abstract
On the model of E.coli - induced acute infectious
peritonitis in rats previously depleted on mast cells of
peritoneal cavity the replacing effects of various doses
of exogenous histamine, serotonin and heparin and
their complex on leukocytic reaction of inflammatory
focus and blood were studied. In was shown that all
of the used substances had a meaning in the mecha-
nisms of modulating effect of mast cells on leukocytes.
The analogous on direction to mast cells` ones effects
on leukocytes were produced mostly by histamine and
especially by the complex of substances.
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