Українська Русский English

ISSN 2522-9028 (Print)
ISSN 2522-9036 (Online)
DOI: https://doi.org/10.15407/fz

Fiziologichnyi Zhurnal

is a scientific journal issued by the

Bogomoletz Institute of Physiology
National Academy of Sciences of Ukraine

Editor: V.F. Sagach

The journal was founded in 1955 as
1955 – 1977 "Fiziolohichnyi zhurnal" (ISSN 0015 – 3311)
1978 – 1993 "Fiziologicheskii zhurnal" (ISSN 0201 – 8489)
1994 – 2016 "Fiziolohichnyi zhurnal" (ISSN 0201 – 8489)
2017 – "Fiziolohichnyi zhurnal" (ISSN 2522-9028)

Fiziol. Zh. 2001; 47(4): 13-18


Changes in the elastolytic system of blood serumand tissue of aorta associated with acid-base imbalance

..M.trofimova, V.E.dosenko, YU.V.byts

    A.A. Bogomoletz National Medical UniversityMinistry of Public Health of Ukraine, Kiev


Abstract

On the model of E.coli - induced acute infectious peritonitis in rats previously depleted on mast cells of peritoneal cavity the replacing effects of various doses of exogenous histamine, serotonin and heparin and their complex on leukocytic reaction of inflammatory focus and blood were studied. In was shown that all of the used substances had a meaning in the mecha- nisms of modulating effect of mast cells on leukocytes. The analogous on direction to mast cells` ones effects on leukocytes were produced mostly by histamine and especially by the complex of substances.

References

  1. Веремеенко К.Н., Голобородько О.П., Кизим А.И.Протеолиз в норме и при патологии. - К.: Здоро-в’я, 1988. - 198 с.
  2. Жалко-Титаренко В.Ф. Водно-электролитныйобмен и кислотно-основное состояние в норме ипри патологии. - К.: Здоров’я, 1989. - 199 с.
  3. Кальнова Л.И. Кислотно-основное состояние. - Вкн. Руководство по клинической лабораторнойдиагностике. - Ч. 3. - Клиническая биохимия /Под ред. М.А.Базарновой, В.Т.Морозовой. - К.:Вища школа, 1986. - С.266-287.
  4. Кришталь М.В. Нейро-гуморальна регуляція ком-пенсаторних реакцій нирок при метаболічномуацидозі: Автореф. дис. ... д-ра мед. наук. – К.,1994. - 43 с.
  5. Bailey J.L., Wang X., England B.K. et al. Theacidosis of chronic renal failure activates muscleproteolysis in rats by augmenting transcription ofgenes encoding proteins of the ATP-dependentІ. М. Трофимова та ін.
  6. 18 ISSN 0201-8489 Фізіол. журн., 2001, Т. 47, № 4ubiquitin-proteasome pathway // J. Clin. Invest. -1996. - 97, N 6. - P.1447-1453.
  7. Ballmer P.E., Imoberdorf R. Influence of acidosison protein metabolism // Nutrition. - 1995. - 11,N 5. - P.462-468.
  8. Balo J. Die mit ammonium-hydroxydvergiftungerzeugbare experimentelle arteriosclerose //Frankfurt. Zschr. f. Path. - 1938. - 52. - P. 205-220.
  9. Brus F., van Oeveren W., Okken A., Oetomo S.B. and activation of circulating polymor-phonuclear leukocytes and platelets are asso-ciated with neonatal respiratory distress syn-drome severity // Pediatrics. - 1997. - 99,N 5. - P.672-680.
  10. 9. England B.K., Jurkovitz C. Effect of glucocorticoidsand extracellular pH on protein metabolism incultured cells // Miner. Electrolyte Metab. - 1992. –18, № 2. – Р. 316-319.
  11. 10. England B.K., Price S.R. Acidosis and gluco-corticoids interact to provoke muscle protein andamino acid catabolism // Blood Purif. - 1995. –13, № 3-4. - Р.147-152.
  12. Greiber S., Mitch W.E. Mechanisms for proteincatabolism in uremia: metabolic acidosis and acti-Нац. мед. ун-т ім. О.О.БогомольцяМ-во охорони здоров’я України, КиївМатеріал надійшовдо редакції 15.12.2000Вплив порушень кислотно-лужного стануvation of proteolytic pathways // Miner. Electro-lyte Metab. - 1992. –18, № 2-5. - Р.233-236.
  13. Lowry O.H., Rosenbrough N.J., Farr A.L. et al.Protein measurement with Folin phenol reagent //J. Biol. Chem. - 1951. - 193. - P.265-275.
  14. May R.C., Masud T., Logue B. et al. Chronicmetabolic acidosis accelerates whole body proteo-lysis and oxidation in awake rats // Kidney Int. -1992. – 41, № 6. - Р.1535-1542.
  15. May R.C., Masud T., Logue B. et al. Metabolicacidosis accelerates whole body protein degradationand leucine oxidation by a glucocorticoid-depen-dent mechanism // Miner. Electrolyte Metab. -1992. – 18, № 2-5. - Р.245-249.
  16. Kunisaki M., Ayukawa K., Oyamada C., OgawaS. A case of non-insulin-dependent diabetes melli-tus associated with diabetic ketoacidosis after theonset of hyperlipidemia and acute pancreatitisfollowing alcohol abuse // Fukuoka Igaku Zasshi.- 1991. – 82, № 8. - Р.464-466.
  17. Tizianello A. Muscle protein turnover in chronicrenal failure patients with metabolic acidosis ornormal acid-base balance // Miner. ElectrolyteMetab. - 1996. – 22, № 1-3. - 58-61.

© National Academy of Sciences of Ukraine, Bogomoletz Institute of Physiology, 2014-2018.