SERUM LEVELS OF ENDOTHELIAL MONOCYTE ACTIVATING PEPTIDE II IN TYPE 1 DIABETES
L.A. Mogylnytska, O.E. Mogylnytska
Khmelnitsky regional hospital
DOI: https://doi.org/10.15407/fz62.01.102
Abstract
Was investigated serum level of endothelial monocyte activating
peptide II (EMAP-II) and endothelium-dependent
dilatation in type 1 diabetes and possible relation between
those. We found an increase serum level of EMAP-II and
decrease of endothelium-dependent dilatation in type 1
diabetes. It was significant correlation between EMAP-II and
HbAc1, blood glucose, total cholesterol, LDL, triglycerides and
inverse correlation between EMAP-II and HDL, endotheliumdependent
dilatation. The revealed change of EMAP-II serum
level reflects an endothelial dysfunction in type 1 diabetes,
alteration of carbohydrate and lipid metabolism could influence
of this pathway.
Keywords:
EMAP-II; diabetes; endothelial dysfunction.
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