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ISSN 2522-9028 (Print)
ISSN 2522-9036 (Online)

Fiziologichnyi Zhurnal

is a scientific journal issued by the

Bogomoletz Institute of Physiology
National Academy of Sciences of Ukraine

Editor-in-chief: V.F. Sagach

The journal was founded in 1955 as
1955 – 1977 "Fiziolohichnyi zhurnal" (ISSN 0015 – 3311)
1978 – 1993 "Fiziologicheskii zhurnal" (ISSN 0201 – 8489)
1994 – 2016 "Fiziolohichnyi zhurnal" (ISSN 0201 – 8489)
2017 – "Fiziolohichnyi zhurnal" (ISSN 2522-9028)

Fiziol. Zh. 2014; 60(4): 105-107

Oxidative stress development in the tissues of salivary glands of rats in conditions of monosodium glutamate-induced obesity

Hordiienko LP1, Berehova TV2, Neporada KS1, Falalieieva TM1

  1. Ukrainian Medical Dental Academy, Poltava, Ukraine
  2. The Institute of Biology, Taras Shevchenko NationalUniversity, Kyiv, Ukraine


Pathogenic mechanisms of damage of salivary glands under obesity are an insufficiently studied problem of modern medicine. On experimental model of obesity induced by monosodium glutamate, free-radical processes and antioxidant defense system were studied in the tissues of salivary glands of rats. Under experimental obesity induced by monosodium glutamate there is a significant increase of the content of thiobarbituric acid reactive substances and a significant decreasе in the activity of superoxide dismutase and catalase. Thus, it indicates to the misbalance of prooxidant and antioxidant systems and the development of oxidative stress. Key words: salivary glands, obesity, monosodium glutamate, oxidative stress.

Keywords: salivary glands, obesity, monosodium glutamate,oxidative stress.


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