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ISSN 2522-9028 (Print)
ISSN 2522-9036 (Online)
DOI: https://doi.org/10.15407/fz

Fiziologichnyi Zhurnal

is a scientific journal issued by the

Bogomoletz Institute of Physiology
National Academy of Sciences of Ukraine

Editor-in-chief: V.F. Sagach

The journal was founded in 1955 as
1955 – 1977 "Fiziolohichnyi zhurnal" (ISSN 0015 – 3311)
1978 – 1993 "Fiziologicheskii zhurnal" (ISSN 0201 – 8489)
1994 – 2016 "Fiziolohichnyi zhurnal" (ISSN 0201 – 8489)
2017 – "Fiziolohichnyi zhurnal" (ISSN 2522-9028)

Fiziol. Zh. 2014; 60(4): 105-107

Oxidative stress development in the tissues of salivary glands of rats in conditions of monosodium glutamate-induced obesity

Hordiienko LP1, Berehova TV2, Neporada KS1, Falalieieva TM1

  1. Ukrainian Medical Dental Academy, Poltava, Ukraine
  2. The Institute of Biology, Taras Shevchenko NationalUniversity, Kyiv, Ukraine
DOI: https://doi.org/10.15407/fz60.04.105


Abstract

Pathogenic mechanisms of damage of salivary glands under obesity are an insufficiently studied problem of modern medicine. On experimental model of obesity induced by monosodium glutamate, free-radical processes and antioxidant defense system were studied in the tissues of salivary glands of rats. Under experimental obesity induced by monosodium glutamate there is a significant increase of the content of thiobarbituric acid reactive substances and a significant decreasе in the activity of superoxide dismutase and catalase. Thus, it indicates to the misbalance of prooxidant and antioxidant systems and the development of oxidative stress. Key words: salivary glands, obesity, monosodium glutamate, oxidative stress.

Keywords: salivary glands, obesity, monosodium glutamate,oxidative stress.

Full text: (PDF, in Ukrainian)

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