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ISSN 2522-9028 (Print)
ISSN 2522-9036 (Online)
DOI: https://doi.org/10.15407/fz

Fiziologichnyi Zhurnal

is a scientific journal issued by the

Bogomoletz Institute of Physiology
National Academy of Sciences of Ukraine

Editor-in-chief: V.F. Sagach

The journal was founded in 1955 as
1955 – 1977 "Fiziolohichnyi zhurnal" (ISSN 0015 – 3311)
1978 – 1993 "Fiziologicheskii zhurnal" (ISSN 0201 – 8489)
1994 – 2016 "Fiziolohichnyi zhurnal" (ISSN 0201 – 8489)
2017 – "Fiziolohichnyi zhurnal" (ISSN 2522-9028)

Fiziol. Zh. 2014; 60(1): 34-40


Dynamics of ischemic skeletal soleus muscle contraction in rats

Khoma OM1, Zavodovs'kyĭ DA1, Nozdrenko DN1, Dolhopolov OV2, Miroshnychenko MS1, Motuziuk OP3.

  1. Taras Shevchenko National University of Kyiv, Ukraine
  2. Institute of Traumatology and Orthopedics NMA Ukraine, Kyiv, Ukraine
  3. Lesya Ukrainka Eastern European National University, Luts'k, Ukraine
DOI: https://doi.org/10.15407/fz60.01.034


Abstract

The processes of change in the rate of generation of power response of artiRcially ischemic muscle using frequency modulated electrical efferent stimulation were investigated. A strain-gauge technique for registration of contraction process was used. Ischemia was induced by ligating main blood vessels of lower extremity. It is shown that ischemia causes a decrease in muscle performance and reduces maximum frequency of the stimulus signal, which leads to the titanic contraction level. It is shown that the lowering of ischemic muscle strength and reduction of the time that needed to establish a steady state de- pended on the time of discharge segment in stimulation pattern.

Keywords: muscle, ischemia, contraction dynamics, power answer

References

  1. Allen D, Lamb G, Westerblad H. Skeletal Muscle Fatigue. Cellular Mechanisms. Physiol Rev. 2008;88(1):287-332. CrossRef PubMed
  2.  
  3. Blick S, Brumback R, Poka A. Compartment syndrome in open tibial fractures. J Bone Jt Surg. 1986;68:1348-53. CrossRef  
  4. Clough T, Baie R. Audit of open tibial diaphyseal fracture management at a district accident . Ann R Coll Surg Engl. 2000;82(6):436-440. PubMed PubMedCentral
  5.  
  6. Dolgopolov O, Nozdrenko D, Strafun S, Miroshnichenko M. Changes in contraction parameters of skeletal muscle due to acute ischemia. Physics of alive. 2010;18(3):64-69.
  7.  
  8. Kostyukov A, Korchak O. Length changes of the cat soleus muscle under frequency-modulated dustributer stimulation of efferents in isotonical conditions. Neuroscience. 1998;82:943-955. CrossRef  
  9. McQueen M, Christie M, Court-Broun M. Acute compartment syndrome in tibial diaphyseal fractures. J Bone Jt Surg. 1996;78(Pt B):95-98.
  10.  
  11. Murdock M, Murdoch M. Compartment syndrome: a review of the literature. Clin Podiatr Med Surg. 2012;29(2):301-310. CrossRef PubMed
  12.  
  13. Nocella M, Colombini B, Benelli G, Cecchi G, Bagni M, Bruton J. Force decline during fatigue is due to both a decrease in the force per individual cross-bridge and the number of cross-bridges. J Physiol. 2011;589(13):3371-81. CrossRef PubMed PubMedCentral
  14.  
  15. Parekh R, Care D, Tainter R. Rhabdomyolysis: advances in diagnosis and treatment. Emerg Med Pract. 2012;14(3):1-15. PubMed
  16.  
  17. Pasquale M, Frykberg E, Tinkoff G. Management of complex extremity trauma. Bull Am Coll Surg. 2006;91(6):36-38. PubMed
  18.  
  19. Pierce S.M. Acute lower extremity compartment syn-drome: avoiding limb loss and long-term complications. Adv NPs PAs. 2012;3(4):21-24. PubMed
  20.  
  21. Schubert A. Exertional compartment syndrome: re-view of the literature and proposed rehabilitation guidelines following surgical release. Int J Sports Phys Ther. 2011;6(2):126-141. PubMed PubMedCentral
  22.  
  23. TrifRtt P, Ktsnig D, Harper W, Barnes M, Allen M, Gregg P. Compartment pressures after closed tibial shaft fracture: their relation to functional outcome. J Bone Jt Surg. 1992;74(Pt B):195-198.
  24.  
  25. Woll T, Duwelius P. The segmental tibial fracture. Clin Orthop Relat Res. 1992;28:204-207. CrossRef  

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