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ISSN 2522-9028 (Print)
ISSN 2522-9036 (Online)
DOI: https://doi.org/10.15407/fz

Fiziologichnyi Zhurnal

is a scientific journal issued by the

Bogomoletz Institute of Physiology
National Academy of Sciences of Ukraine

Editor-in-chief: V.F. Sagach

The journal was founded in 1955 as
1955 – 1977 "Fiziolohichnyi zhurnal" (ISSN 0015 – 3311)
1978 – 1993 "Fiziologicheskii zhurnal" (ISSN 0201 – 8489)
1994 – 2016 "Fiziolohichnyi zhurnal" (ISSN 0201 – 8489)
2017 – "Fiziolohichnyi zhurnal" (ISSN 2522-9028)

Fiziol. Zh. 2013; 59(6): 37-42


Characteristization of the human microencapsulated adrenal cortex tissue in long-term culture

Paster IP, Levchuk NI, Tron'ko MD

    V.P. Komisarenko Institute of Endocrinology and Metabolism of the NAMS of Ukraine”, Kyiv, Ukraine
DOI: https://doi.org/10.15407/fz59.06.037

Abstract

Microencapsulated human adrenal cortex tissue preserves the ability to secrete 11-oxycorticosteroids for 51 days of cultivation, and to react adequately in responses to stimulation with adrenocorticotrophin and inhibition with chloditane, suggesting good prospects of the use of this tissue for compensation of the hypofunctional state of adrenocorticotropin system in experimental animals.

Keywords: Adrenal cortex, microencapsulation, cultivation, 11-oxycorticosteroids, adrenocorticotrophin, chloditane.

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