Українська English

ISSN 2522-9028 (Print)
ISSN 2522-9036 (Online)
DOI: https://doi.org/10.15407/fz

Fiziologichnyi Zhurnal

is a scientific journal issued by the

Bogomoletz Institute of Physiology
National Academy of Sciences of Ukraine

Editor-in-chief: V.F. Sagach

The journal was founded in 1955 as
1955 – 1977 "Fiziolohichnyi zhurnal" (ISSN 0015 – 3311)
1978 – 1993 "Fiziologicheskii zhurnal" (ISSN 0201 – 8489)
1994 – 2016 "Fiziolohichnyi zhurnal" (ISSN 0201 – 8489)
2017 – "Fiziolohichnyi zhurnal" (ISSN 2522-9028)

Fiziol. Zh. 2001; 47(2): 66-69

Сell zinc metabolism in pancreatic isletsand hippocampus on the action of physiologicaland extreme irritants

V. A. Eshchenko, V. D. Bovt, M. M. Malko, A. V. Prohvatilova,O. M. Kuchkovsky

    Zaporozye State University



Abstract

Zinc content in pancreatic islet cells and hippocampus was studied with the aid of highly sensitive selective cytochemical reaction of 8-(p-toluensulfonylamino)-quinoline. It was shown that the factors stimulating B-insulocyte secretory activity induced the decrease of this metal concentrations in the cell. An increase of these cells zinc content observed in the cases of their secretory activity inhibition. The extreme irritants induced two phase changes of zinc concentrations in pancreatic islets and hippocampus.

Full text: (PDF, in Ukrainian)

References

  1. СПИСОК ЛІТЕРАТУРИ
  2. Ещенко В.А. Гистохимическое исследование цинка // Цитология. — 1978. — №8.— С. 927-933.
  3. Панин Л.Е. Биохимические механизмы стресса. — Новосибирск: Наука, 1983.— 234 с.
  4. Соколовский В.В. Гистохимические исследования в токсикологии. — Л.: Медицина, 1971. — 172 с.
  5. Хейхоу Ф.Г.Дж., Кваглино Д. Гематологическая цитохимия: Пер. с англ. — М.: Медицина, 1983. — 319 c.
  6. Bettger W.J., O’Dell L.L. A critical physiological role of zinc in the structure and function of biomembranes // Life Sci. — 1981. — 28. — P. 1405-1438.
  7. Bray T., Bettger W.J. The physiological role of zinc as an antioxidant // Free Radic. Biol. Med. — 1990. — 8. — P. 281-291.
  8. Chausmer A.B. Zinc, insulin and diabetes // J. Am. Coll. Nutr. — 1998. — 17. — P.109-115.
  9. Fabris N. Zinc, nervous system and aging // Aging (Milano). — 1997. — 9. — P. 28-29.
  10. 9. Gibson R.S. Zinc: a critical nutrient in growth and development // N. Z. Med. J. — 1998. — 111. — P. 63-64.
  11. 10. Huang E.P. Metal ions and synaptic transmission: think zinc // Proc. Natl. Acad. Sci. USA. — 1997. — 94. — P. 13386-13387.
  12. Thurnbam D.J. Micronutritients and immune function: some recent developments // J. Clin. Pathol. — 1997. — 50. — P. 887-891.
  13. Szerdahelyi P., Kasa P. Histochemistry of zinc and copper // Intern. Rev. Cythol. — 1984. — 89. — P. 1-33.
  14. Vallee B.L. Zinc: biochemistry, physiology, toxicology and clinical pathology // Biofactors. — 1988. — 1. — P. 31-36.
  15. Vallee B.L., Auld D.S. Zinc coordination, function and structure of zinc enzymes and other proteins // Biochemistry. — 1990. — 19. — P. 5647-5659.
© National Academy of Sciences of Ukraine, Bogomoletz Institute of Physiology, 2014-2024.