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ISSN 2522-9028 (Print)
ISSN 2522-9036 (Online)
DOI: https://doi.org/10.15407/fz

Fiziologichnyi Zhurnal

is a scientific journal issued by the

Bogomoletz Institute of Physiology
National Academy of Sciences of Ukraine

Editor-in-chief: V.F. Sagach

The journal was founded in 1955 as
1955 – 1977 "Fiziolohichnyi zhurnal" (ISSN 0015 – 3311)
1978 – 1993 "Fiziologicheskii zhurnal" (ISSN 0201 – 8489)
1994 – 2016 "Fiziolohichnyi zhurnal" (ISSN 0201 – 8489)
2017 – "Fiziolohichnyi zhurnal" (ISSN 2522-9028)

Fiziol. Zh. 2013; 59(5): 50-55


The activity of the interneuron pools of the spinal cord in experimental diabetes mellitus

Rodyns'kyĭ OH, Zinov'ieva OH, Mozhunov OV, Trushenko OS

    Dnipropetrovsk Medical Academy of the Ministry of PublicHealth, Ukraine
DOI: https://doi.org/10.15407/fz59.05.050

Abstract

We analyzed threshold, chronaxy and parameters of the potential of the dorsal surface (PDP) of the spinal cord (SC) in Wistar rats with experimental diabetes mellitus (DM) and intact animals. We found a decrease in the excitation threshold by 41.4% (P < 0.05), and an increase in chronaxia by 9.5% (P < 0.01), an increase of the amplitude of the N3-component by 15.8% (P < 0.05), and an increase in the duration of the afferent peak by 4.5 % (P < 0,05) and the N2-component by 10.9% (P < 0.01) responsively. We conclude that the metabolic changes under DM lead to modification of activity of the afferent pathways and interneuron pool of SC.

Keywords: diabetes mellitus, interneuronal pool, potential ofthe dorsal surface of the spinal cord.

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