Українська Русский English

ISSN 2522-9028 (Print)
ISSN 2522-9036 (Online)
DOI: https://doi.org/10.15407/fz

Fiziologichnyi Zhurnal

is a scientific journal issued by the

Bogomoletz Institute of Physiology
National Academy of Sciences of Ukraine

Editor-in-chief: V.F. Sagach

The journal was founded in 1955 as
1955 – 1977 "Fiziolohichnyi zhurnal" (ISSN 0015 – 3311)
1978 – 1993 "Fiziologicheskii zhurnal" (ISSN 0201 – 8489)
1994 – 2016 "Fiziolohichnyi zhurnal" (ISSN 0201 – 8489)
2017 – "Fiziolohichnyi zhurnal" (ISSN 2522-9028)

Fiziol. Zh. 2013; 59(3): 65-71


The influence of normobaric hypoxia on the morphofunctional changes of thyroid gland in young rats

Ianko RV

    Bogomoletz Institute of physiology NAS of Ukraine, Kyiv, Ukraine
DOI: https://doi.org/10.15407/fz59.03.065

Abstract

We investigated the influence of hypoxic gas mixture (the different modes) on the morphometric indexes of thyroid gland functional activity in 3-mounth rats. It was shown a decrease in the size of follicles of middle area and the colloid and an increase in the amount of thyrocytes in a follicle, resorption vacuoles and interfollicular epithelium after exposure to hypoxic gas mixture (10% oxygen). We also detected an increase in a follicle-colloid index and a decrease in the colloid accumulation index. Thus, a dosed normobaric hypoxia intensifies the functional activity and physiological regeneration processes of thyroid gland in the young animals.

Keywords: hypoxic gas mixture, thyroid gland

References

  1. Berezovskii V.A. Prirodnaya i instrumental'naya oroterapiya. Donetsk: Zaslavskii, 2012. 304 p.
  2.  
  3. Berezovs'kii V.Ya., Yanko R.V., Litovka I.G., Zamors'ka T.M., Chaka O.G. Vpliv dozovanoi normobarichnoi gipoksii na morfologichni pokazniki stanu parenhimi shchitovidnoi zalozi . Ukr. morfol. al'manah. 2011. 9, N 3. P. 38-40.
  4.  
  5. Vasil'eva E.V. Vliyanie prerivistoi gipobaricheskoi gipoksii na morfofunktsional'nie izmeneniya shchitovidnoi zhelezi u kris v norme i pri eksperimental'noi disfunktsii: avtoref. diss. kandidata biologicheskih nauk: spets. 03.00.13 Ul'yanovsk, 2009. 23 p.
  6.  
  7. Vasil'eva E.V., Tararak T.Ya., Vasil'eva N.A., Balikin N.V. Vliyanie prerivistoi gipobaricheskoi gipoksii na morfofunktsional'nie izmeneniya shchitovidnoi zhelezi . Vestn. Tverskogo gos. un-ta. Seriya: Biologiya i ekologiya. 2008. N 8. P. 8-13.
  8.  
  9. Volkova O.V., Eletskii Yu.K. Osnovi gistologii s gistologicheskoi tehnikoi. M.: Meditsina, 1982. 304 p.
  10.  
  11. Zabrodin V.A. Morfologiya shchitovidnoi zhelezi i metodi ee izucheniya: metodicheskie rekomendatsii. Smolensk: SGMA, 2005. 37 p. Nikishin D.V. Morfologiya i metodi issledovaniya shchitovidnoi zhelezi: metodicheskie rekomendatsii. Penza: Inform.-izdat. tsentr PGU, 2008. 64 p.
  12.  
  13. Sabanova R.K. Izmenenie ionov ioda v shchitovidnoi zheleze pri interval'no-ritmicheskoi gipoksii . Uspehi sovr. estestvoznaniya. 2006. N 3. P. 43-44.
  14.  
  15. Hem A. Gistologiya T. V. M: Mir., 1983. 294 p.
  16.  
  17. Joe G., Shashank R. J. Drugs and thyroid . JAPI. 2007. 55. P. 215-223.
  18.  
  19. Kolchinskaya A.Z. Mechanisms of interval hypoxic training effects . Hypoxia Med. J. 1993. 1. P. 5.
  20.  
  21. Monazani F., Lawler J.M., Powers S.K. Thyroid hormone action on intermediary metabolism . Can. J. Appl. Physiol. 1998. 23, N l. P. 23-55.
  22.  
  23. Powell F.L., Garcia N. Physiological effects of intermittent hypoxia . High. lt. Med. Biol. 2002. N 1. P. 125-136.
  24.  
  25. Sawhney R.C., Malhotra A.S. Thyroid function during intermittent exposure to hypobaric hypoxia . Int. J. Biometeorol. 2010. 34, N 3. R. 161-163.
  26.  
  27. Tararak T.J., Vasileva V.V., Balykin M.V. Restructuring of the thyroid gland in primary hypothyroidism under the influence of intermittent hypobaric hypoxia . Bul. Exp. Biol. and Med. 2010. 145, N 5. R. 647-649.
  28.  
  29. Yaluan M, Freitag P., Zhou J. Thyroid hormone induces erythropoietin gene expression through augmented accumulation of hypoxia-inducible factor-1a . Regu Physiol. 2004. 287, N 3. R. 600-607.
  30.  

© National Academy of Sciences of Ukraine, Bogomoletz Institute of Physiology, 2014-2019.