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ISSN 2522-9028 (Print)
ISSN 2522-9036 (Online)
DOI: https://doi.org/10.15407/fz

Fiziologichnyi Zhurnal

is a scientific journal issued by the

Bogomoletz Institute of Physiology
National Academy of Sciences of Ukraine

Editor-in-chief: V.F. Sagach

The journal was founded in 1955 as
1955 – 1977 "Fiziolohichnyi zhurnal" (ISSN 0015 – 3311)
1978 – 1993 "Fiziologicheskii zhurnal" (ISSN 0201 – 8489)
1994 – 2016 "Fiziolohichnyi zhurnal" (ISSN 0201 – 8489)
2017 – "Fiziolohichnyi zhurnal" (ISSN 2522-9028)

Fiziol. Zh. 2001; 47(2): 32-40


Ionic currents responsible for excitability ofisolated rat retinal isolated ganglion cells

N. N. Veselovskaya, N.S. Veselovsky

    Kiev Center of Eye Pathology; А. А. Bogomoletz Institute of PhysiologyNational Academy of Sciences of Ukraine, Kiev


Abstract

Ionic currents responsible for excitability of retinal ganglion cells (RGC) freshly isolated from eyes of adult rats were studied. Outward potassium currents in RGC represented by populations of slow inactivating and non-inactivating currents. Inward Н. М. Веселовська, М. С. Веселовський 40 ISSN 0201-8489 Фізіол. журн., 2001, Т. 47, № 2 sodium currents were completely blocked by extracellular application of 0.25 мM TTX. Calcium conductance in freshly isolated RGC has two components: low- and high-threshold. Extracellular application of nifedipine (10 мM) or Cd2+ (10 мM) blocked high threshold calcium currents by 28% and 60%, correspondingly, without any significant effect on low threshold calcium currents

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© National Academy of Sciences of Ukraine, Bogomoletz Institute of Physiology, 2014-2018.